Some have currently been researched as prospect medicines, but They are really opioids, belonging to the identical class of compounds as morphine and hydrocone.Szpakowska et al. also examined conolidone and its motion about the ACKR3 receptor, which aids to elucidate its Beforehand unfamiliar mechanism of motion in both of those acute and Long-term

Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors in the central anxious procedure, conolidine modulates alternate molecular targets. A Science Developments analyze identified that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR